Prednisolone is a steroidal drug which is indicated in reducing inflammation and in reducing symptoms in various disorders like, rheumatoid arthritis and severe cases of asthma. It is also indicated in primary or secondary adrenal cortex insufficiency. The content of Prednisolone is Prednisone. Prednisone is a white, odorless, crystalline powder which is mildly soluble in water, in alcohol, in chloroform, in dioxane, and in methanol. Prednisolone is used to suppress the immune system and inflammation.
Prednisolone can make it tough for the physician to diagnose the actual disorder as it can mask few of the signs of an infection. Prednisolone is contraindicated in persons who suffer with systemic fungal infections and in those persons who are hypersensitive to the contents of Prednisolone.
Long-term high doses of Prednisolone can produce Cushing's syndrome hence, prolonged use of high doses of Prednisolone should be avoided. Immediate medical attention should be sought off in cases of overdose of Prednisolone.
An increased dose of Prednisolone shall be required by the patient before, during, and after any stressful situation, in case the patient has been taking Prednisolone for a long period of time. A temporary increase of dose shall always be administered when any stress is anticipated.
Patients who are on Prednisolone therapy for prolonged periods should always wear or carry identification.
In alternate-day therapy of Prednisolone, the "resting day" is provided so that the adrenal glands get a chance to produce some hormone naturally so that they shall attain their ability.
In case you are taking several doses of Prednisolone a day, then you must take the missed dose as soon as you remember and then continue with your regular schedule but in case you fail to remember until your next dose, then you can double the dose that you take.

Prednisolone should always be taken along with food, to prevent stomach upset. The quantity of dose is dependent on the condition that has to be treated and the response of the patient to the drug. The starting dose can vary from 5 milligrams to 60 milligrams a day. The dose can be lowered, when response is attained.
In case treatment with Prednisolone is recommended for longer periods then, alternate day therapy, can be prescribed. The dose has to be gradually reduced over several days or weeks.

Few side effects experienced by the patients on Prednisolone are congestive heart failure; Hypertension; Muscle weakness; Steroid myopathy; Pathologic fracture of long bones; Peptic ulcer with possible perforation and hemorrhage; Pancreatitis; Abdominal distention; etc.

• Phenobarbital.
• Phenytoin.
• Rifampin.
• Troleandomycin.
• Ketoconazole.
• Aspirin.
• Oral anticoagulants.

Prednisolone is indicated in treating abnormal adrenal gland development; Allergic conditions; Blood disorders; Certain cancers; Flare-ups of multiple sclerosis; Fluid retention due to "nephrotic syndrome"; Lung diseases, including tuberculosis; Meningitis; Rheumatoid arthritis and related disorders; Skin diseases; Thyroid gland inflammation, etc.

Prednisolone should be stored far from light and moisture and at room temperature between 59-86 degrees F (15-30 degrees C). It should also be stored away from children and pets.

Prednisolone should be taken in consultation with doctor and this medication should be avoided:
• If you ever had an allergic reaction to it.
• In case you have had a body-wide fungus infection, such as candidiasis or cryptococcosis.